11B.11 MONOCLONAL ANTIBODY


Antibody Specificity:   Mouse IL-4

Isotype:   Rat IgG1

Buffer:   Sodium Phosphate and Sodium Chloride, pH 6.8

Inventory Number:
88092601 - 16.5 mg/ml, 0.2 ml/vial (total 3.3 mg/vial)
00022901 - 17.5 mg/ml, 1.15 ml/vial (total 20 mg/vial)

Product Testing:
MAP: Cell Line Negative Purity by HPLC: > 95%
Mycoplasma: Cell Line Negative Sterility: Pass
Endotoxin: <1.0 EU/mg

Product Storage:   -70oC

Cell Line Origin:   Dr. William Paul, NIH

Bioactivity:
In vitro - 10 ug of 11B.11 will neutralize 2000 units (1 ng) of murine IL-4.

In vivo - 5 mg of 11B.11 per week per mouse will significantly reduce endogenous IL-4 levels in most experimental situations.

References:   Nature 315:33 (1985)


CAUTION:FOR RESEARCH USE ONLY. NOT FOR DRUG OR DIAGNOSTIC USE. NOT FOR USE IN HUMANS.

11B.11 is aliquoted in 3 mg and 20 mg amounts and are available to investigators with peer-reviewed support, at institutions, and at commercial establishments. Use of these materials is limited solely to in vivo and in vitro basic research studies.

NOTE: Recipients of bulk cytokines and monoclonal antibodies will be required to sign a Material Transfer Agreement. All International Orders are required to pay a packaging and handling fee. All recipients are required to providea a FedEx account number. All recipients are required to pay for shipping.