| 11B.11 MONOCLONAL ANTIBODY
Antibody Specificity: Mouse IL-4
Isotype: Rat IgG1
Buffer: 50mM Sodium Phosphate and 300mM Sodium Chloride, pH 6.
Lot Number: L0412006
Inventory Number: 05060201
Concentration: 21.2 mg/ml, 0.27 ml/vial (total 5.7 mg/vial)
Product Storage: -70oC
- Product Testing:
-
| MAP:
| Cell Line Negative |
|
Purity by HPLC:
| > 95% |
| Mycoplasma:
| Cell Line Negative |
|
Bioburden:
| 0 CFU/ml
|
| Endotoxin:
| 1.54 EU/mg
|
Bioactivity:
| In vitro: |
|
0.9 ng/ml 11B.11 neutralizes 86.8% 500 pg/ml IL-4 |
| |
|
9.0 ng/ml 11B.11 neutralizes 96.3% 500 pg/ml IL-4 |
| |
|
90 ng/ml 11B.11 neutralizes >97% 500 pg/nl IL-4 |
| |
| In vivo: |
|
5 mg of 11B.11 per week per mouse will significantly reduce endogenous IL-4 levels in most experimental situations. |
Cell Line Origin: Dr. William Paul, NIH
References: Nature 315:33 (1985)
CAUTION:FOR RESEARCH USE ONLY. NOT FOR DRUG OR DIAGNOSTIC USE. NOT FOR USE IN HUMANS.
11B.11 is available to investigators with peer-reviewed support, at institutions, and at commercial establishments. Use of these materials is limited solely to in vivo and in vitro basic research studies.
NOTE: Recipients of bulk cytokines and monoclonal antibodies will be required to sign a Material Transfer Agreement that is auto-generated by our web program, following the electronic submission of an order. All international requesters and commercial establishments are required to pay a packaging and handling fee. An invoice will be emailed for these charges. All recipients are required to provide a FedEx account number. All recipients are required to pay for shipping. |