This stock resulted from the selective inbreeding by Dr. Leslie Webster using foundation animals from a large colony of Swiss mice maintained at Rockefeller Institute following importation from Switzerland in 1926. To Carworth from Rockefeller Institute. Highly inbred at the time they were acquired by Carworth. This line was reduced to a single pair and progeny outbred from that point forward to form a new stock. To Charles River in 1974 from a representative cross section of the Carworth CFW colony. The Swiss Webster mouse has been used extensively for decades as an all purpose strain for research and drug safety testing. Swiss Webster females are also ideal pseudopregnant recipients for embryo transfers of black and agouti mouse lines. |
