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Animal Production Program

  01C38 CBA/J

Origin and Characteristics: In 1920, Strong developed the CBA inbred strain from a cross of a Bagg albino female and a DBA male. CBA was selected for a low incidence of mammary tumors. Strong sent the CBA mice to Andervont in 1947. Andervont sent the CBA mice to The Jackson Laboratory in 1948. Received by NCI from Jackson Laboratories in 1983. CBA/J inbred mice are widely used as a general purpose strain. CBA/J strain is the only CBA substrain that carries the Pde6brd1 mutation, which causes blindness by wean age.