Monday, November 16, 2009
12:45 p.m. Welcome
and Introductions
Gordon
Hager, NCI
Munira Basrai; NCI
Beth Sullivan; Duke University
Session I: Kinetochores and
chromosome movement
Moderator: Ben Black
1:00 p.m. "Kinetochore-microtubule
attachments"
Todd Stukenberg; University
of Virginia
1:30 p.m. "The Nup107-160 complex and ?-TuRC regulate
microtubule polymerization at kinetochores"
Mary Dasso; NICHD
2:00 p.m. “SENP2 localization controls sumoylation of
kinetochore- and centromere-associated proteins"
Michael J.
Matunis; Johns Hopkins University
2:30 p.m. "Roles for cytoplasmic dynein in chromosome movement
and the spindle assembly checkpoint”
Kevin
T. Vaughan; University of Notre Dame
3:00 p.m. Break
Session II: Checkpoints, silencing, and
synthetic centromeres
Moderator:
Barbara Mellone
3:30 p.m. "Tension and occupancy in the spindle checkpoint”
Daniel
Burke; University of Virginia
4:00 p.m. "Diverse roles of HP1 proteins in centromeric
silencing and functions in fission yeast”
Shiv Grewal; NCI
4:30 p.m. "Sequence-independent inheritance of pericentromeric
heterochromatin in S. pombe”
Kristin C. Scott;
Duke University
5:00 p.m. "Chromosomal
translocation genetics supports centromere’s role in mitotic selective sister
chromatid segregation constituting a mechanism for asymmetric cell division and
development”
Amar J.S. Klar; NCI
5:30 p.m. "Human artificial
chromosomes with a predefined structure for kinetochore study and gene
expression”
Vladimir
Larionov; NCI
6:00 p.m. Dinner
at Natcher Conference Center
Tuesday, November 17, 2009
Session III:
Identity and assembly of centromeric chromatin
Moderator: Kristin Scott
8:30 a.m. "Centromeric histone H3 variant structure and
dynamics in human cancer cells"
Yamini
Dalal; NCI
9:00 a.m. “The contribution of CENP-A-containing nucleosomes to
centromere identity and function”
Ben Black; University of Pennsylvania
9:30 a.m. "Coordinated recruitment of CENP-A, CAL1 and CENP-C
during mitosis in Drosophila"
Barbara Mellone; University of Connecticut
10:00 a.m. “HJURP mediated regulation
of CENP-A centromeric chromatin assembly"
Daniel R. Foltz; University of Virginia
10:30 a.m. Break
Session IV: Identity and assembly of
centromeric chromatin II
Moderator:
Dan Burke
11:00 a.m. "Molecular
mechanisms regulating localization of centromeric histone H3 variant Cse4p and
kinetochore function”
Munira Basrai; NCI
11:30 a.m. "Architecture of the centromeric nucleosome in
budding yeast”
Carl Wu; NCI
12:00 p.m. "The geometry of centromeric chromatin”
Kerry Bloom;
University of North Carolina-Chapel Hill
12:30 p.m. Lunch break and poster viewing
Session V:
Sequence-dependent and epigenetic mechanisms of centromere assembly
Moderator: Yamini Dalal
2:30 p.m. "Epigenetic analysis of human neocentromeres”
Peter
E. Warburton; Mount Sinai School of Medicine
3:00 p.m. “Centromere assembly and organization on dicentric
human chromosomes”
Beth A. Sullivan; Duke University
3:30 p.m. “Chasing codes for human
centromeres: the case for alpha satellite”
Huntington F.
Willard; Duke University
4:00 p.m. "Kinetochore protein architecture: protein copy
number per kinetochore microtubule”
E. D. Salmon;
University of North Carolina-Chapel Hill
4:30 p.m. Meeting
wrap-up session
5:00 p.m. Adjourn
