Scientific Program
| October 1st, Morning Session | |
| Introductions | |
| 8:15am | Robert Wiltrout Director, Center for Cancer Research, National Cancer Institute |
| 8:20 | John Niederhuber Director, National Cancer Institute |
| 8:25 | Jon Ashwell Chief, Laboratory of Immune Cell Biology, Center for Cancer Research,National Cancer Institute |
| Session I: Lymphocyte Development and Function | |
| Chairperson - Larry Samelson | |
| 8:30 | Al Singer "How TCR specificity is determined in the thymus" |
| 9:00 | Remy Bosselut "Transcriptional control of CD4-CD8 lineage differentiation" |
| 9:30 | Hyun Park "Cytokine signaling and CD4/CD8 lineage choice during T cell development in the thymus" |
| 9:45 - 10:15 | Break |
| 10:15 | Jon Ashwell "Maintenance and reversibility of the memory T cell state of readiness" |
| 10:45 | Marc Jenkins "How CD4+ T cells sense and remember bacterial infection" |
| 11:15 | Crystal Mackall "Regulation of CD4 homeostasis by IL7Ra+ dendritic cells" |
| 11:45 | Scott Durum "T cells seek IL-7 for life" |
| 12:15 - 1:30pm | Lunch |
| October 1st, Afternoon Session | |
| Session II: Signaling Pathways and Molecular Mechanisms | |
| Chairperson - Remy Bosselut
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| 1:30pm | Ron Germain Dynamic intravital imaging of the immune system" |
| 2:00 | Zheng-gang Liu "The molecular mechanism of TNF signaling" |
| 2:30 | Murty Srinivasula "Autophagy in innate immunity" |
| 2:45 | Ann-Marie Pendergast "Abl tyrosine kinases in T cell signaling and function" |
| 3:15 - 3:45 | Break |
| 3:45 | Larry Samelson "Signaling at the T cell antigen receptor" |
| 4:15 | Wendell Lim "The evolution and engineering of signaling pathways" |
| 4:45 | Pam Schwartzberg "Regulation of T helper subsets: Lessons from primary immunodeficiencies" |
| 5:15 - 7:00 PM | Poster Session |
| October 2nd, Morning Session | |
| Session III: Immunity and Disease | |
| Chairperson - Al Singer | |
| 8:30am | Lou Staudt "Immune regulatory mechanisms coopted by lymphoid malignancies" |
| 9:00 | Giorgio Trinchieri "Innate resistance, inflammation, cell cancer" |
| 9:30 | Andre Nussenzweig "Maintaining genome stability in lymphocytes" |
| 10:00 | Triantafyllos Chavakis "Regulation of leukocyte recruitment and vascular inflammation" |
| 10:15 - 10:45 | Break |
| 10:45 | Phil Greenberg "T cell tumor therapy: overcoming obstacles to targeting self-proteins expressed by the tumor" |
| 11:15 | Carl June "Evolving strategies for adoptive T cell transfer therapy" |
| 11:45 | Jim Allison "Immune checkpoint blockade in cancer therapy: new insights and opportunities" |
| 12:15pm | Adjourn |
