Frontiers In Basic Immunology
September 28-29, 2006


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Sponsorship of this meeting is through the Center of Excellence in Immunology, Center for Cancer Research, National Cancer Institute.
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Frontiers In Basic Immunology
Conference Program

September 28–29, 2006
Masur Auditorium, Blg 10
National Institutes of Health, Bethesda, MD
(Also being videocast to Lipsett Auditorium)

       
Thursday, September 28, 2006
       
WELCOME  
  8:30 – 8:45am Robert Wiltrout, Director, CCR
    John Neiderhuber, Acting Director, NCI
       
Session 1: Lymphoid Cell Development and Differentiation – Chair: Jon Ashwell
       
  8:45 -  9:15 Laurie Glimcher
    "XBP-1, Plasma Cell Differentiation and the Unfolded Protein Response"
       
  9:15  -   9:45 Harinder Singh
    "Gene Regulatory Networks Orchestrating Cell Fates in the Immune System"
       
  9:45  - 10:15 Andre Nussenzweig
    "Maintaining Genomic Stability in Lymphocytes"
       
  10:15  - 10:45  BREAK
       
  10:45  - 11:15 Juan Zuniga-Pflucker
    "Induction of T Cell Development, Notch is not Enough"
       
  11:15  - 11:45 Al Singer
    "Thymic selection and T cell homeostasis"
       
  11:45  - 12:15 Remy Bosselut
    "Nuclear Effectors of CD4-CD8 Lineage Differentiation"
       
LUNCH  (12:15 - 2:00)
       
Session 2: Cell Signaling and Effector Function–Chair: Al Singer
       
  2:00  -   2:30 Craig Thompson
    "How Lymphocytes Meet the Metabolic Demands of Mitogenic Stimulation." 
       
  2:30  -   3:00  Sankar Ghosh
    "Regulation of NF-kB in Immune and Inflammatory Responses"
       
  3:00  -   3:30 Jon Ashwell
    "Recognition of K63-Linked Polyubiquitin: A Key Event in NF-κB Activation"
       
  3:30  -   4:00 BREAK
       
  4:00  -   4:30 Larry Samelson
    "Signaling Complexes at the TCR"
       
  4:30  -   5:00 Scott Durum
    "IL-7 in the Life, Death and Proliferation of Lymphocytes"
       
  5:00  -   5:30 Tom Waldmann
    "Disordered Cytokine/Cytokine Receptor Expression in T-Cell Leukemia/Lymphoma: Targets for Immunotherapy"
       
Poster Session (5:30 - 7:30)
       
Friday, September 29, 2006
       
Session 3:  Cellular and Innate Immunity-Chair: Larry Samelson
       
  8:30  -   9:00 Jeff Bluestone
    "Balancing Immunity - Negative Regulation is the Key"
       
  9:00  -   9:30  Alberto Mantovani
    "Pentraxins in the Interplay Between Cellular and Humoral Innate Immunity"
       
  9:30  - 10:00 Chris Biron
    "Mapping In Vivo Interferon Signaling and Its Regulation"
       
  10:00  - 10:30  BREAK
     
  10:30  - 11:00 Giorgio Trinchieri
    "Toll-like Receptors, Cancer and Inflammation"
       
  11:00  - 11:30 Joost Oppenheim
    "Alarmins are Novel Cytokines"
       
  11:30  - 12:00 Mary Carrington
    "The Innate Partnership of Multiple HLA and KIR Combinations Against HIV-1" 
       

Program Committee

  • Alfred Singer, MD
  • Jonathan Ashwell, MD
  • Larry Samelson, MD
  • Ron Gress, MD
  • Joost Oppenheim, MD
  • Scott Durum, PhD
  • William Farrar, PhD
  • John Ortaldo, PhD